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Title: Disulfiram- Its Use in Alcohol Dependence and Other Disorders
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Although Disulfiram’s mechanism of action in alcohol dependence was long thought to be its effects as a psychological deterrent, more recent studies point to potential anti-craving effects as well

Although Disulfiram’s mechanism of action in alcohol dependence was long thought to be its effects as a psychological deterrent, more recent studies point to potential anti-craving effects as well. The book also discusses the use of Disulfiram across diverse populations along with monitoring for compliance and various adverse effects that may manifest

Although Disulfiram’s mechanism of action in alcohol dependence was long thought to be its effects as a psychological deterrent, more recent studies point to potential anti-craving effects as well.

Although Disulfiram’s mechanism of action in alcohol dependence was long thought to be its effects as a psychological deterrent, more recent studies point to potential anti-craving effects as well. The book also discusses the use of Disulfiram across diverse populations along with monitoring for compliance and various adverse effects that may manifest.

Background: Preoperative alcohol and other recreational substance use (ORSU) may catalyze perioperative complications. Accordingly, interventions aiming to reduce preoperative substance use are warranted. Although disulfiram’s mechanism of action in alcohol dependence was long thought to be its effects as a psychological deterrent, more recent studies have uncovered potential anti-craving effects as well.

Alcohol and Alcoholism- Effects on Brain and Development

Alcohol and Alcoholism- Effects on Brain and Development. Posted in Ebooks Posted in Ebooks.

The test was designed to be used internationally, and was validated in a study drawing patients from six countries.

Alcohol abuse and dependence frequently occur with other psychiatric conditions; this dual diagnosis is called comorbidity. Professionals working with comorbid patients face unique and challenging dilemmas about how to provide the best treatment to address both conditions.

KEYWORDS Disulfiram; Alcohol Dependence; Alcohol; Deterrent .

KEYWORDS Disulfiram; Alcohol Dependence; Alcohol; Deterrent; Pharmacotherapy; Long Acting Disulfiram. 5. DISULFIRAM USE IN ADOLESCENTS WITH ALCOHOL DEPENDENCE In a first of its kind double-blind placebo-controlled study of disulfiram, 26 adolescents aged 16 - 19 years with chronic or episodic alcohol dependence were recruited and put on either disulfiram or placebo.

In alcohol dependence, reduction of alcohol, as defined within DSM-IV, can be attained by learning to control the use of alcohol

In alcohol dependence, reduction of alcohol, as defined within DSM-IV, can be attained by learning to control the use of alcohol. That is, a client can be offered a social learning approach that helps them to 'cope' with external pressures by re-learning their pattern of drinking alcohol.

The key features of alcohol dependence and harmful use are listed in Box . Alcohol use was reduced by 70–80% in the disulfiram group compared with 50% in placebo group.

The key features of alcohol dependence and harmful use are listed in Box 1. About 5% of the UK population are dependent on alcohol (Farrell et al, 2001) and 8 million Britons drink more than recommended levels. Box 1 Alcohol dependence and harmful use. Key features1 of ICD–10 dependence include:, Compulsion to drink. Fifty-five per cent of participants adhered to the protocol.

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English | ISBN: 9813298758 | 2019 | 77 pages | EPUB, PDF | 2 MB + 1383 KB
This book focuses on the value of supervised Disulfiram therapy, highlighting the many potential and unique benefits of Disulfiram. One of the oldest drugs available for the long-term management of alcohol dependence, Disulfiram remains a viable treatment option for alcohol dependence and has been shown in recent studies to be more successful in treating patients with alcohol dependence than Naltrexone, Topiramate and Acamprosate. It is also useful in dual diagnosis patients and those with co-morbid cocaine and alcohol dependence. Although Disulfiram’s mechanism of action in alcohol dependence was long thought to be its effects as a psychological deterrent, more recent studies point to potential anti-craving effects as well.
In dedicated chapters, the book reviews major clinical trials of Disulfiram spanning nearly 60 years, its historical aspects and discovery, side effects, treatment protocols and uses in the context of alcohol dependence. The book also discusses the use of Disulfiram across diverse populations along with monitoring for compliance and various adverse effects that may manifest. Further topics include Disulfiram implant therapy and the role of Disulfiram in the modern long-term pharmacotherapy of alcohol dependence, as well as the role of cognitive behavior therapy in enhancing the effects of Disulfiram and the emerging role of Disulfiram in treating cocaine dependence and pathological gambling. As such, the book offers a “one-stop” comprehensive guide to all aspects of Disulfiram therapy.
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